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1. What we have now shown is that the Filaggrin defect is there for people who have peanut allergy but who don't have eczema, which shows a clear link between Filaggrin and peanut allergy.
2. Filaggrin gene is a member of epidermal differentiation complex, and it closely relates to the formation of cell membrane and terminal differentiation of epidermis.
3. He added that as Filaggrin defects were found in only 20% of the peanut allergy cases, there was still a lot of work to be done to understand fully the genetic link to the allergy.
4. Their research discovered that the Filaggrin gene helped to make the skin a good barrier against irritants and allergens.
5. Dr Sara Brown, a fellow at Dundee University, said investigating whether Filaggrin was a cause of peanut allergy was the "logical next step" after a link with eczema and asthma had been established.
6. The specific target of the immune response in rheumatoid arthritis is filaggrin.
7. Those with the defect can be three times more likely to suffer peanut allergy than people with normal Filaggrin.
8. 'Clear link'The study suggests one in five of all peanut allergy sufferers have a Filaggrin defect.
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